Kinase affinity due to PTM flanking sequence alterations

Kinases are known to recognize specific motifs surrounding Y, S, and T residues, and these motifs can be used to predict kinase interactions using a tool called Kinase Library. Here, we will use Kinase Library to identify kinases who may have a stronger preference for the flanking sequences of PTMs in one isoform vs. another.

Note

The optional dependency kinase-library is required to run this example. You can install it using pip install kinase-library.